Elcatonin Explained

thumb|ElcatoninElcatonin is a calcitonin derivative used as an anti-parathyroid agent.

It is transformed from eel's calcitonin by changing the S-S bond into a stable C-N bond. It inhibits the absorption and autolysis of bones and thus leads to lowering of blood calcium. It inhibits bone salts from dissolving and transferring and promotes the excretion of calcium and phosphorus in the urine. It inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at a normal level. It is mainly used for remitting or eliminating pain caused by osteoporosis.^{[1] [2]}

Notes and References

1. Yoh K, Uzawa T, Orito T, Tanaka K . Improvement of Quality of Life (QOL) in Osteoporotic Patients by Elcatonin Treatment: A Trial Taking the Participants' Preference into Account . Japanese Clinical Medicine . 3 . 9–14 . 2012 . 23946680 . 3738553 . 10.4137/JCM.S8291 .
2. Tanaka S, Yoshida A, Kono S, Oguma T, Hasegawa K, Ito M . 21904979 . Effectiveness of elcatonin for alleviating pain and inhibiting bone resorption in patients with osteoporotic vertebral fractures . Journal of Bone and Mineral Metabolism . 35 . 5 . 544–553 . September 2017 . 27830386 . 10.1007/s00774-016-0791-6 .