EggNOG (database) explained
| eggNOG |
| Description: | Database of orthologous proteins and functional annotations at multiple taxonomical levels. |
| Center: | European Molecular Biology Laboratory |
| Author: | Huerta-Cepas et al. |
| Citation: | Huerta-Cepas et al. (2015) |
| Released: | 2015 |
| Url: | http://eggnogdb.embl.de |
The eggNOG database is a database of biological information hosted by the EMBL. It is based on the original idea of COGs (clusters of orthologous groups)[1] [2] and expands that idea to non-supervised orthologous groups constructed from numerous organisms.[3] The database was created in 2007[4] and updated to version 4.5 in 2015.[5] eggNOG stands for evolutionary genealogy of genes: Non-supervised Orthologous Groups.
References
- Tatusov RL, Koonin EV, Lipman DJ . A genomic perspective on protein families . Science . 278 . 5338 . 631–7 . 1997 . 9381173 . 10.1126/science.278.5338.631 . 1997Sci...278..631T .
- Tatusov RL, Galperin MY, Natale DA, Koonin EV . The COG database: a tool for genome-scale analysis of protein functions and evolution . Nucleic Acids Res. . 28 . 1 . 33–6 . 2000 . 10592175 . 102395 . 10.1093/nar/28.1.33 .
- Powell . Sean . Szklarczyk, Damian . Trachana, Kalliopi . Roth, Alexander . Kuhn, Michael . Muller, Jean . Arnold, Roland . Rattei, Thomas . Letunic, Ivica . Doerks, Tobias . Jensen, Lars J . von Mering, Christian . Bork, Peer . January 2012 . eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges . Nucleic Acids Research . 40 . D1 . D284–D289 . 22096231 . 10.1093/nar/gkr1060 . 3245133.
- Jensen LJ, Julien P, Kuhn M, von Mering C, Muller J, Doerks T, Bork P . eggNOG: automated construction and annotation of orthologous groups of genes . Nucleic Acids Res. . 36 . Database issue . D250–4 . 2008 . 17942413 . 2238944 . 10.1093/nar/gkm796 .
- Huerta-Cepas J, Szklarczyk D, Forslund K, Cook H, Heller D, Walter MC, Rattei T, Mende DR, Sunagawa S, Kuhn M, Jensen LJ, von Mering C, Bork P . eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences . Nucleic Acids Res. . 44 . D1 . D286–93 . 2016 . 26582926 . 4702882 . 10.1093/nar/gkv1248 .
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