| Efraín Sánchez | |
| Fullname: | Efraín Elías Sánchez Casimiro |
| Birth Date: | 26 February 1926 |
| Birth Place: | Barranquilla, Colombia |
| Death Place: | Bogotá, Colombia |
| Position: | Goalkeeper |
| Years1: | 1944 |
| Years2: | 1945 |
| Years3: | 1946 |
| Years4: | 1947–1949 |
| Years5: | 1950 |
| Years6: | 1951 |
| Years7: | 1952 |
| Years8: | 1953–1954 |
| Years9: | 1955–1957 |
| Years10: | 1958–1960 |
| Years11: | 1960–1963 |
| Years12: | 1964[1] |
| Clubs1: | Millonarios |
| Clubs2: | Once Caldas |
| Clubs3: | La Fortuna |
| Clubs4: | San Lorenzo |
| Clubs5: | América de Cali |
| Clubs6: | Deportivo Cali |
| Clubs7: | Junior |
| Clubs8: | Santa Fe |
| Clubs9: | Medellín |
| Clubs10: | Atlas |
| Clubs11: | Medellín |
| Clubs12: | Millonarios |
| Nationalyears1: | 1947–1962 |
| Nationalteam1: | Colombia |
| Manageryears1: | 1963 |
| Managerclubs1: | Colombia |
| Manageryears2: | 1975 |
| Managerclubs2: | Colombia |
| Manageryears3: | 1983–1984 |
| Managerclubs3: | Colombia |
Efraín Elías "El Caimán" Sánchez Casimiro (26 February 1926 – 16 January 2020) was a Colombian footballer who played as goalkeeper. He competed for the Colombia national football team at the 1962 FIFA World Cup which was held in Chile. Among other teams, he played for San Lorenzo of Argentina in the 1940s. He won the Colombian league title three times during his career.
Sánchez played for Mexican side Club Atlas in 1959.[2]
After retiring as a player Sánchez went into management, taking charge of the Colombia national team on three occasions.