Edward John Wherry III explained

Edward John Wherry III (known professionally as John Wherry) is an American immunologist. He is the Richard and Barbara Schiffrin President's Distinguished Professor and department chair of Systems Pharmacology and Translational Therapeutics at the University of Pennsylvania. He is also the director of the Penn Institute for Immunology.[1]

E. John Wherry III
Doctoral Advisor:Laurence Eisenlohr
Discipline:Immunology
Website:https://www.med.upenn.edu/wherrylab/

Education

Wherry received his B.S. degree in science from The Pennsylvania State University in 1993 and his Ph.D. in immunology from Thomas Jefferson University in 2000.[2] He completed his thesis on the effect of epitope density on CD8+ cell priming under the mentorship of Laurence "Ike" Eisenlohr.[3] [4]

Academic posts

Wherry continued on to a postdoctoral fellowship with Rafi Ahmed at Emory University from 2000 to 2004.[5] After completing his postdoc, he joined The Wistar Institute as an assistant professor where he remained until 2010. He then joined the department of Microbiology at the University of Pennsylvania's Perelman School of Medicine. He served as the chair of the Immunology Graduate Group (IGG) from 2011 to 2013 and remains on the IGG Executive Committee. In 2012 he was appointed as director of the Institute for Immunology (IFI).[6] Wherry was named the inaugural Richard and Barbara Schiffrin President's Distinguished Professor in 2017.[7] A year later, Wherry was appointed as chair of the Systems Pharmacology and Translational Therapeutics department.[8]

Research

Wherry's research has focused on the field of T cell exhaustion, elucidating mechanisms that attenuate T cell responses during chronic infections and cancer. His discoveries include characterizing several immunological checkpoints and T cell states that can be targeted to re-invigorate exhausted T cells. Wherry's lab has played a prominent role in understanding the concept of human immune health using high-dimensional, integrative, translational immunology approaches.[9]

Awards and honors

External links

Notes and References

  1. Web site: Wherry Lab. The Trustees of the University of Pennsylvania. 2020-12-13.
  2. Web site: E. John Wherry, PhD . The Trustees of the University of Pennsylvania . December 13, 2020.
  3. Distinguished Alumni Award Lecture . Thomas Jefferson University . April 25, 2013. Jefferson Digital Commons. December 13, 2020. Wherry . PhD .
  4. Web site: 2000 Commencement for Jefferson Medical College and College of Graduate Studies . Thomas Jefferson University . June 9, 2000. Jefferson Digital Commons. December 13, 2020.
  5. Web site: Molecular basis of t cell exhaustion: Insights for immunotherapy . Elsevier Inc. . 2017 . Cell Symposia: Cancer, Inflammation, and Immunity . December 13, 2020.
  6. Web site: Molecular basis of t cell exhaustion: Insights for immunotherapy . Elsevier Inc. . 2017 . Cell Symposia: Cancer, Inflammation, and Immunity . December 13, 2020.
  7. Web site: E. John Wherry: Richard and Barbara Schiffrin President's Distinguished Professor. The University of Pennsylvania Almanac . January 10, 2017 . University of Pennsylvania Almanac . December 13, 2020.
  8. Web site: Immunologist Named Chair of Systems Pharmacology. Penn Medicine . July 23, 2018 . Penn Medicine News . December 13, 2020.
  9. Web site: Appointment of E. John Wherry, PhD, as Chair of the Department of Systems Pharmacology and Translational Therapeutics . Jameson . J. Larry . June 26, 2018 . Perelman School of Medicine . December 13, 2020.
  10. Web site: Stand Up To Cancer Encourages "Innovation in Collaboration" through Grants to Research Teams . Entertainment Industry Foundation . March 28, 2018 . Stand Up to Cancer . December 13, 2020.
  11. Web site: Frederick W. Alt Award. . December 13, 2020.
  12. Web site: The World's Most Influential Scientific Minds 2014. Reuters/Tony Gentile. April 2014 . . December 13, 2020.
  13. Distinguished Alumni Award Lecture . Thomas Jefferson University . April 25, 2013. Jefferson Digital Commons. December 13, 2020. Wherry . PhD .
  14. Web site: Molecular basis of t cell exhaustion: Insights for immunotherapy . Elsevier Inc. . 2017 . Cell Symposia: Cancer, Inflammation, and Immunity . December 13, 2020.
  15. Web site: Preparing for the next flu pandemic--manmade or natural . Kirk . Margaret O. . The Wistar Institute . 2006 . Summer 2006 FOCUS . December 13, 2020.

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