| Honorific Prefix: | Captain |
| Edward Henry Columbine | |
| Birth Date: | 2 July 1763 |
| Birth Place: | Westminster |
| Death Date: | 18 June 1811 |
| Death Place: | HMS Crocodile, at sea |
| Allegiance: | Kingdom of Great Britain |
| Branch: | Royal Navy |
| Serviceyears: | 1778–1811 |
| Rank: | Captain |
| Commands: | HMS Resolution HMS Ulysses West Africa Squadron HMS Solebay HMS Crocodile |
| Known For: | Hydrography Anti-slavery operations |
| Battles: | |
| Alma Mater: | The King's School, Canterbury |
| Spouse: | |
Captain Edward Henry Columbine (2 July 1763 – 18 June 1811) was an English naval officer and hydrographer who served as Governor of Sierra Leone from 12 February 1810 – May 1811.
Columbine was given command of HMS Resolution in 1792–1796 and participated in the Battle of Genoa, 14 March 1795.[1]
Columbine had already been appointed alongside William Dawes and Thomas Ludlam to carry out a review of the forts and Settlements in British West Africa when Lord Castlereagh asked him to take over a governor of Sierra Leone from Thomas Perronet Thompson.[2] Whilst Dawes and Ludlam proceeded to inspect settlements along the West African Coast, Columbine stayed in Sierra Leone to deal with the colonies affairs.[2]