| Eduardo Charme | |
| Birth Date: | 1854 10, df=y |
| Birth Place: | Talca, Chile |
| Death Place: | Santiago, Chile |
| Nationality: | Chilean |
| Office1: | President of the Senate of the Republic of Chile |
| Term Start1: | 15 May 1915 |
| Term End1: | 10 May 1918 |
| Predecessor1: | Silvestre Ochagavía Echaurren |
| Successor1: | Ismael Tocornal |
| Party: | Independent Liberal Party |
| Occupation: | Politician |
| Profession: | Physician |
Eduardo Charme Fernández (born 8 October 1954 – 10 October 1920) was a Chilean politician and physician who served as President of the Senate of Chile.