| Building Name: | Grand Synagogue of Edirne Adrianople Synagogue |
| Native Name: | Edirne Büyük Sinagogu |
| Native Name Lang: | tr |
| Map Type: | Turkey |
| Map Size: | 200 |
| Location: | Maarif St. 10, Edirne, Turkey |
| Geo: | 41.6716°N 26.5516°W |
| Religious Affiliation: | Orthodox Judaism |
| Rite: | Sephardi |
| Province: | Edirne |
| Functional Status: | Active |
| Architect: | France Depré |
| Architecture: | yes |
| Architecture Style: | Moorish Revival |
| Groundbreaking: | 1906 |
| Year Completed: | 1909 |
| Construction Cost: | 1,200 gold coins |
| Capacity: | 1,200 |
Grand Synagogue of Edirne, aka Adrianople Synagogue (Turkish: Edirne Büyük Sinagogu) is a historic Sephardi synagogue located in Maarif Street of Edirne, Turkey. It was designed in the Moorish Revival style and restored in 2015.
The destroyed more than 1,500 houses and also damaged several synagogues in the city. The twenty-thousand strong Jewish community urgently needed a place of worship. Following the permission of the Ottoman Government and the edict of Sultan Abdul Hamid II, the construction of a new synagogue began on January 6, 1906, at the site of the ruined synagogues Mayor and Pulya in Suriçi (Citadel) neighborhood. It was designed by the French architect France Depré in the architectural style of the Sephardi Leopoldstädter Tempel in Vienna, Austria. Costing 1,200 gold coins, it was opened to service on the eve of Pesach (Passover) in April 1909. Capable of accommodating up to 1,200 worshipers (900 men and 300 women), it was Europe's third-largest temple and the largest in Turkey.
In 1983, the synagogue was abandoned after most of the Jewish community left the city, emigrating to Israel, Europe, or North America. In 1995, the temple by law came under the control of the governmental Turkish Foundations Institution.
The abandoned and ruined synagogue as well as its outbuilding were restored by the Turkish Foundations Institution in five years, spending 5,750,000 (approximately US$2.5 million). On March 26, 2015, the synagogue was reopened with a celebration and a Shacharit, morning prayer service, attended by a large number of Jews including Ishak Ibrahimzadeh (leader of the Jewish community in Turkey), Rav Naftali Haleva, deputy to Hakham Bashi (Chief Rabbi) Ishak Haleva, Bülent Arınç, Deputy Prime Minister of Turkey, and some other Turkish high officials. The worship was overseen by Rabbi David Azuz, who had led the service on the closing day 36 years before. The Municipality of Edirne hung a banner in the street of the synagogue and greeted the guests with the words "Welcome home, our old neighbors".