| Ed Sixsmith | |
| Position: | Catcher |
| Bats: | Right |
| Throws: | Right |
| Birth Date: | 26 February 1863 |
| Birth Place: | Philadelphia |
| Death Place: | Philadelphia |
| Debutleague: | MLB |
| Debutdate: | September 11 |
| Debutyear: | 1884 |
| Debutteam: | Philadelphia Quakers |
| Finalleague: | MLB |
| Finaldate: | September 11 |
| Finalyear: | 1884 |
| Finalteam: | Philadelphia Quakers |
| Statleague: | MLB |
| Stat1label: | Batting average |
| Stat1value: | .000 |
| Stat2label: | Runs |
| Stat2value: | 0 |
| Stat3label: | Runs batted in |
| Stat3value: | 0 |
| Teams: | |
Edward Sixsmith (February 26, 1863 – December 12, 1926) was a baseball player who played catcher in the Major Leagues in one game for the 1884 Philadelphia Quakers. He appeared in his game on September 11, 1884 and failed to record a hit in two at-bats. He played minor league ball from 1884–1888.