| Ed Matesic | |
| Birth Date: | November 6, 1907 |
| Birth Place: | Marshall County, West Virginia, U.S. |
| Death Date: | June 4, 1988 |
| Death Place: | Wheeling, West Virginia, U.S. |
| Number: | 12, 47 |
| Position1: | Halfback, Quarterback |
| Height Ft: | 6 |
| Height In: | 1 |
| Weight Lb: | 198 |
| College: | Pittsburgh |
| High School: | Benwood High School |
| Playing Years1: | (1934–1935) |
| Playing Team1: | Philadelphia Eagles |
| Playing Years2: | (1936) |
| Playing Team2: | Pittsburgh Pirates |
| Statlabel1: | Passing yards |
| Statvalue1: | 1,412 |
| Statlabel2: | Pass attempts |
| Statvalue2: | 262 |
| Statlabel3: | TD–INT |
| Statvalue3: | 8–34 |
| Statlabel4: | Pass completions |
| Statvalue4: | 99 |
| Statlabel5: | Rushing yards |
| Statvalue5: | 377 |
| Databasefootball: | MATESED01 |
Edward J. Matesic (November 6, 1907 – June 4, 1988) was an American football player for the Philadelphia Eagles and the Pittsburgh Pirates. Led the University of Pittsburgh in interceptions in 1931. In 1931 only the statistics of yards and touchdowns were recorded and not the number of interceptions. In 1931 Ed had 91 yards and one touchdown on interceptions. Then played HB/TB in the pros. Was the Pittsburgh Pirates starting quarterback in 1936. Pirates later became the Pittsburgh Steelers. In his pro career, Matesic threw for 1,412 yards and 8 touchdowns, ran for 377 yards and 1 touchdown, and caught 4 passes for 51 yards and one touchdown.