| Ed Duffy | |
| Position: | Shortstop |
| Bats: | Unknown |
| Throws: | Right |
| Birth Date: | c. 1844 |
| Birth Place: | Ireland |
| Death Place: | Brooklyn, New York |
| Debutleague: | MLB |
| Debutdate: | May 8 |
| Debutyear: | 1871 |
| Debutteam: | Chicago White Stockings |
| Finalleague: | MLB |
| Finaldate: | October 30 |
| Finalyear: | 1871 |
| Finalteam: | Chicago White Stockings |
| Statleague: | MLB |
| Stat1label: | Batting average |
| Stat1value: | .231 |
| Stat2label: | Home runs |
| Stat2value: | 0 |
| Stat3label: | RBI |
| Stat3value: | 15 |
| Teams: |
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Edward Charles Duffy (c. 1844 - October 16, 1888) was an Irish-born professional baseball player. He played one season in Major League Baseball as an infielder in 1871 for the Chicago White Stockings. He was banned from baseball in 1865 for associating with gamblers, but was reinstated in 1870.