| Ed Cole | |
| Position: | Pitcher |
| Bats: | Right |
| Throws: | Right |
| Birth Date: | 22 March 1909 |
| Birth Place: | Wilkes-Barre, Pennsylvania |
| Death Place: | Nashville, Tennessee |
| Debutleague: | MLB |
| Debutdate: | April 22 |
| Debutteam: | St. Louis Browns |
| Finalleague: | MLB |
| Finaldate: | September 24 |
| Finalteam: | St. Louis Browns |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 1–7 |
| Stat2label: | Earned run average |
| Stat2value: | 5.31 |
| Stat3label: | Strikeouts |
| Stat3value: | 31 |
| Teams: |
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Edward William Cole (born Edward William Kisleauskas, March 22, 1909 – July 28, 1999) was a Major League Baseball pitcher who played for the St. Louis Browns in and .