Ecklonia stolonifera explained

Ecklonia stolonifera (Japanese: ツルアラメ, turuarame) is a brown alga species in the genus Ecklonia found in the Sea of Japan. It is an edible species traditionally eaten in Japan.^[1]

Chemistry

Phlorotannins

Ecklonia stolonifera contains the phlorotannins phlorofucofuroeckol A,^[2] eckol, dieckol,^[3] dioxinodehydroeckol^[4] (eckstolonol),^[5] 2-phloroeckol, phlorofucofuroeckol B, 6,6'-bieckol,^[6] triphlorethol-A,^[7] phloroglucinol and 7-phloroeckol.^[8]

Those phlorotannins are responsible for the potent pharmacological effects associated with this seaweed.^[9] These molecules show a hepatoprotective activity.^{[6] [10]}

Oxylipins

The oxylipins ecklonialactones A, B,^[11] C, D, E and F^[12] and fucosterol^[7] can also be isolated from the species.

External links

• algaebase.org

Notes and References

1. 10.1016/j.foodchem.2006.09.042. Varieties of antioxidant and antibacterial properties of Ecklonia stolonifera and Ecklonia kurome products harvested and processed in the Noto peninsula, Japan. 2007. Kuda. Takashi. Kunii. Taeko. Goto. Hideyuki. Suzuki. Takamoto. Yano. Toshihiro. Food Chemistry. 103. 3. 900.
2. 21963823. 2011. Kim. AR. Lee. MS. Shin. TS. Hua. H. Jang. BC. Choi. JS. Byun. DS. Utsuki. T. Ingram. D. Kim. HR. Phlorofucofuroeckol a inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAPK. 25. 8. 1789–95. 10.1016/j.tiv.2011.09.012. Toxicology in Vitro.
3. 20422362. 2010. Goo. HR. Choi. JS. Na. DH. Quantitative determination of major phlorotannins in Ecklonia stolonifera. 33. 4. 539–44. 10.1007/s12272-010-0407-y. Archives of Pharmacal Research. 26981463 .
4. 19443227. 2009. Shim. SY. Choi. JS. Byun. DS. Inhibitory effects of phloroglucinol derivatives isolated from Ecklonia stolonifera on Fc(epsilon)RI expression. 17. 13. 4734–9. 10.1016/j.bmc.2009.04.050. Bioorganic & Medicinal Chemistry.
5. 12913249. 2003. Kang. HS. Chung. HY. Jung. JH. Son. BW. Choi. JS. A new phlorotannin from the brown alga Ecklonia stolonifera. 51. 8. 1012–4. Chemical & Pharmaceutical Bulletin. 10.1248/cpb.51.1012. free.
6. 10.1021/jf300157w. 22587607. Isolation and Identification of Phlorotannins from Ecklonia stolonifera with Antioxidant and Hepatoprotective Properties in Tacrine-Treated HepG2 Cells. 2012. Lee. Min-Sup. Shin. Taisun. Utsuki. Tadanobu. Choi. Jae-Sue. Byun. Dae-Seok. Kim. Hyeung-Rak. Journal of Agricultural and Food Chemistry. 60. 21. 5340–9.
7. 10.1111/j.1444-2906.2006.01288.x. Angiotensin-converting enzyme I inhibitory activity of phlorotannins from Ecklonia stolonifera. 2006. Jung. Hyun Ah. Hyun. Sook Kyung. Kim. Hyeung Rak. Choi. Jae Sue. Fisheries Science. 72. 6. 1292. 42869137 .
8. 10.1111/j.1444-2906.2007.01511.x. Acetyl- and butyrylcholinesterase inhibitory activities of sterols and phlorotannins from Ecklonia stolonifera. 2008. Yoon. Na Y. Chung. Hae Y. Kim. Hyeung R. Choi. Jae S. Fisheries Science. 74. 200–207. 24337383 .
9. 10.1007/s12272-010-0407-y. Quantitative determination of major phlorotannins in Ecklonia stolonifera. 2010. Goo. Hyun Ryul. Choi. Jae Sue. Na. Dong Hee. Archives of Pharmacal Research. 33. 4. 539–44. 20422362. 26981463 .
10. 10.1007/BF02977904. Hepatoprotective constituents of the edible brown algaEcklonia stolonifera on tacrine-induced cytotoxicity in hep G2 cells. 2005. Kim. Youn Chul. An. Ren Bo. Yoon. Na Young. Nam. Taek Jeong. Choi. Jae Sue. Archives of Pharmacal Research. 28. 12. 1376–80. 16392671. 25793794 .
11. 10.1021/np50103a028. The Absolute Configuration of Ecklonialactones A, B, and E, Novel Oxylipins from Brown Algae of the Genera Ecklonia and Egregia. 1994. Todd. James S.. Proteau. Philip J.. Gerwick. William H.. Journal of Natural Products. 57. 171–4. 8158161. 1.
12. 10.1016/0031-9422(93)85413-L. Ecklonialactones-C-F from the brown alga Ecklonia stolonifera. 1993. Kurata. Kazuya. Taniguchi. Kazuya. Shiraishi. Kazunari. Suzuki. Minoru. Phytochemistry. 33. 155–159.