| Eastern Creek | |
| Subdivision Type1: | Country |
| Subdivision Name1: | Australia |
| Subdivision Type2: | State |
| Subdivision Name2: | New South Wales |
| Subdivision Type3: | Region |
| Subdivision Name3: | Sydney basin (IBRA), Greater Western Sydney |
| Subdivision Type5: | Local government areas |
| Subdivision Name5: | Cumberland, Fairfield, Blacktown |
| Length: | 30km (20miles) |
| Source1: | below Sugarloaf Ridge |
| Source1 Location: | near |
| Source1 Coordinates: | -33.8632°N 150.8607°W |
| Source1 Elevation: | 116m (381feet) |
| Mouth: | confluence with South Creek |
| Mouth Coordinates: | -33.6438°N 150.8276°W |
| Mouth Elevation: | 3m (10feet) |
| River System: | Hawkesbury-Nepean catchment |
| Basin Size: | 36.22km2 |
| Tributaries Left: | Reedy Creek, Angus Creek, Bells Creek |
| Tributaries Right: | Bungarribee Creek, Breakfast Creek, Burdekin Creek, Quakers Creek |
| Custom Label: | Nature reserve |
| Custom Data: | Nurragingy Reserve |
| Extra: | [1] |
Eastern Creek, a watercourse that is part of the Hawkesbury-Nepean catchment, is located in Greater Western Sydney, New South Wales, Australia.
Eastern Creek rises in the western suburbs of Sydney, below Sugarloaf Ridge at Western Sydney Regional Park about west by north of . The creek flows generally north, joined by the Reedy, Angus, Bungarribee, Breakfast, Burdekin, Quakers, and Bells creeks, before reaching its confluence with South Creek, in the suburb of . The creek descends over its course.[1]
Eastern Creek is transversed by the M4 Western Motorway and the Great Western Highway between and ; and the Western railway line west of .