| Earl's Sluice | |
| Subdivision Type1: | Country |
| Subdivision Name1: | England |
| Subdivision Type3: | Counties |
| Subdivision Name3: | Greater London |
| Subdivision Type4: | Districts / Boroughs |
| Subdivision Type5: | Towns |
| Subdivision Name5: | Deptford |
| Source1: | Ruskin Park |
| Source1 Location: | Denmark Hill |
| Source1 Coordinates: | 51.4667°N -0.0925°W |
| Mouth: | River Thames |
| Mouth Location: | Deptford Wharf |
| Mouth Coordinates: | 51.4931°N -0.032°W |
| Tributaries Right: | River Peck |
Earl's Sluice is an underground river in south-east London, England. Its source is Ruskin Park on Denmark Hill. In South Bermondsey it is joined by the River Peck before emptying into the Thames at Deptford Wharf.
Earl's Creek marks the boundary between St Mary's parish, Rotherhithe and St Paul's parish, Deptford and their successors the London Borough of Southwark and the London Borough of Lewisham. It also marks the boundary between the historic counties of Kent and Surrey.[1] The river is named after the Earl of Gloucester in the time of Henry I.