| Country: | ARE |
| Type: | E |
| Route: | 22 |
| Length Km: | 125 |
| Direction A: | West |
| Direction B: | East |
| Terminus A: | Al Mafraq Bridge |
| Junction: |
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| Terminus B: | Khalifa bin Zayed Street |
| Cities: | Abu Dhabi, Al Ain |
E 22 (Arabic: شارع ﺇ 22), is a major highway in the Emirate of Abu Dhabi, United Arab Emirates (UAE). The road travels between the emirates's biggest cities of Abu Dhabi and Al Ain, and is called simply, Al Ain Road (Arabic: شارع العين). The west end of the road starts at Al Mafraq Bridge in the Rabdan area in Abu Dhabi, runs across the desert of Al Wathba, and ends in the west end of Khalifa bin Zayed Street in Al Salmat, Al Ain. The speed limit ranges from 100 to 160 km/h, and is 160 km/h on most parts of the road[1]