EXOC8 explained

Exocyst complex component 8 is a protein that in humans is encoded by the EXOC8 gene.^{[1] [2]}

Interactions

EXOC8 has been shown to interact with RALB.^[3]

Further reading

• Kee Y, Yoo JS, Hazuka CD, Peterson KE, Hsu SC, Scheller RH . Subunit structure of the mammalian exocyst complex . Proc. Natl. Acad. Sci. U.S.A. . 94 . 26 . 14438–43 . 1998 . 9405631 . 25013 . 10.1073/pnas.94.26.14438 . free . 1997PNAS...9414438K .
• Hsu SC, Hazuka CD, Roth R, Foletti DL, Heuser J, Scheller RH . Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments . Neuron . 20 . 6 . 1111–22 . 1998 . 9655500 . 10.1016/S0896-6273(00)80493-6 . 10915358 . free .
• Brymora A, Valova VA, Larsen MR, Roufogalis BD, Robinson PJ . The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene . J. Biol. Chem. . 276 . 32 . 29792–7 . 2001 . 11406615 . 10.1074/jbc.C100320200 . free.
• Inoue M, Chang L, Hwang J, Chiang SH, Saltiel AR . The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin . Nature . 422 . 6932 . 629–33 . 2003 . 12687004 . 10.1038/nature01533 . 2003Natur.422..629I . 2027.42/62982 . 4395760 . free .
• Wang S, Hsu SC . Immunological characterization of exocyst complex subunits in cell differentiation . Hybrid. Hybridomics . 22 . 3 . 159–64 . 2004 . 12954101 . 10.1089/153685903322286575 .
• Moskalenko S, Tong C, Rosse C, Mirey G, Formstecher E, Daviet L, Camonis J, White MA . Ral GTPases regulate exocyst assembly through dual subunit interactions . J. Biol. Chem. . 278 . 51 . 51743–8 . 2004 . 14525976 . 10.1074/jbc.M308702200 . free .
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .

Notes and References

1. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc Natl Acad Sci U S A . 99 . 26 . 16899–903 . Dec 2002 . 12477932 . 139241 . 10.1073/pnas.242603899 . 2002PNAS...9916899M . free .
2. Web site: Entrez Gene: EXOC8 exocyst complex component 8.
3. Moskalenko S, Tong C, Rosse C, Mirey G, Formstecher E, Daviet L, Camonis J, White MA . Ral GTPases regulate exocyst assembly through dual subunit interactions . J. Biol. Chem. . 278 . 51 . 51743–8 . Dec 2003 . 14525976 . 10.1074/jbc.M308702200 . free .