Enah/Vasp-like explained

Ena/VASP-like protein is a member of the Ena/VASP family of proteins that in humans is encoded by the EVL gene.^{[1] [2] [3]}

Further reading

• Andersson B, Wentland MA, Ricafrente JY . A "double adaptor" method for improved shotgun library construction. . Anal. Biochem. . 236 . 1 . 107–13 . 1996 . 8619474 . 10.1006/abio.1996.0138 . etal.
• Yu W, Andersson B, Worley KC . Large-scale concatenation cDNA sequencing. . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146. etal.
• Ohta S, Mineta T, Kimoto M, Tabuchi K . Differential display cloning of a novel rat cDNA (RNB6) that shows high expression in the neonatal brain revealed a member of Ena/VASP family. . Biochem. Biophys. Res. Commun. . 237 . 2 . 307–12 . 1997 . 9268706 . 10.1006/bbrc.1997.7113 .
• Krause M, Sechi AS, Konradt M . Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. . J. Cell Biol. . 149 . 1 . 181–94 . 2000 . 10747096 . 10.1083/jcb.149.1.181 . 2175102. etal.
• Hu RM, Han ZG, Song HD . Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. . Proc. Natl. Acad. Sci. U.S.A. . 97 . 17 . 9543–8 . 2000 . 10931946 . 10.1073/pnas.160270997 . 16901. 2000PNAS...97.9543H . etal. free .
• Scott MP, Zappacosta F, Kim EY . Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1. . J. Biol. Chem. . 277 . 31 . 28238–46 . 2002 . 12029088 . 10.1074/jbc.M202783200 . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241. 2002PNAS...9916899M . etal. free .
• Salazar MA, Kwiatkowski AV, Pellegrini L . Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. . J. Biol. Chem. . 278 . 49 . 49031–43 . 2004 . 14506234 . 10.1074/jbc.M308104200 . etal. free .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Beausoleil SA, Jedrychowski M, Schwartz D . Large-scale characterization of HeLa cell nuclear phosphoproteins. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446. 2004PNAS..10112130B . etal. free .
• Krause M, Leslie JD, Stewart M . Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics. . Dev. Cell . 7 . 4 . 571–83 . 2004 . 15469845 . 10.1016/j.devcel.2004.07.024 . etal. free .
• Lafuente EM, van Puijenbroek AA, Krause M . RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion. . Dev. Cell . 7 . 4 . 585–95 . 2004 . 15469846 . 10.1016/j.devcel.2004.07.021 . etal. 1721.1/83508 . free .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928. etal.
• Rotter B, Bournier O, Nicolas G . AlphaII-spectrin interacts with Tes and EVL, two actin-binding proteins located at cell contacts. . Biochem. J. . 388 . Pt 2 . 631–8 . 2005 . 15656790 . 10.1042/BJ20041502 . 1138971. etal.
• Barzik M, Kotova TI, Higgs HN . Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins. . J. Biol. Chem. . 280 . 31 . 28653–62 . 2005 . 15939738 . 10.1074/jbc.M503957200 . 1747414. etal. free .
• Rual JF, Venkatesan K, Hao T . Towards a proteome-scale map of the human protein-protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 . etal.
• Bournier O, Kroviarski Y, Rotter B . Spectrin interacts with EVL (Enabled/vasodilator-stimulated phosphoprotein-like protein), a protein involved in actin polymerization. . Biol. Cell . 98 . 5 . 279–93 . 2006 . 16336193 . 10.1042/BC20050024 . etal. free .
• Bausen M, Fuhrmann JC, Betz H, O'sullivan GA . The state of the actin cytoskeleton determines its association with gephyrin: role of ena/VASP family members. . Mol. Cell. Neurosci. . 31 . 2 . 376–86 . 2006 . 16376568 . 10.1016/j.mcn.2005.11.004 . 24824029 .

Notes and References

1. Lambrechts A, Kwiatkowski AV, Lanier LM, Bear JE, Vandekerckhove J, Ampe C, Gertler FB . cAMP-dependent protein kinase phosphorylation of EVL, a Mena/VASP relative, regulates its interaction with actin and SH3 domains . J Biol Chem . 275 . 46 . 36143–51 . Dec 2000 . 10945997 . 10.1074/jbc.M006274200 . free .
2. Klostermann A, Lutz B, Gertler F, Behl C . The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain . J Biol Chem . 275 . 50 . 39647–53 . Jan 2001 . 10993894 . 10.1074/jbc.M006316200 . free .
3. Web site: Entrez Gene: EVL Enah/Vasp-like.