Sterol 14-demethylase | |
Organism: | Saccharomyces cerevisiae |
Taxid: | 4932 |
Symbol: | ERG11 |
Altsymbols: | CYP51F1 |
Entrezgene: | 856398 |
Homologene: | 55488 |
Refseqmrna: | NM_001179137 |
Refseqprotein: | NP_011871 |
Uniprot: | P10614 |
Ecnumber: | 1.14.14.154 |
Chromosome: | VIII |
Entrezchromosome: | NC_001140 |
Genloc Start: | 120091 |
Genloc End: | 121683 |
ERG11 or Sterol 14-demethylase is a fungal cytochrome P450 enzyme originally from Saccharomyces cerevisiae, belongs to family CYP51, with the CYP Symbol CYP51F1.[1] ERG11 catalyzes the C14-demethylation of lanosterol to 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol which is the first step of biosynthesis of the zymosterol, zymosterol will be further converted into Ergosterol.[2]