ERF (gene) explained

ETS domain-containing transcription factor ERF is a protein that in humans is encoded by the ERF gene.^{[1] [2] [3]}

Further reading

• Liu D, Pavlopoulos E, Modi W, Moschonas N, Mavrothalassitis G . ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes . Oncogene . 14 . 12 . 1445–51 . March 1997 . 9136988 . 10.1038/sj.onc.1200965 . free .
• Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G . Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation . Molecular and Cellular Biology . 19 . 6 . 4121–33 . June 1999 . 10330152 . 104371 . 10.1128/mcb.19.6.4121.
• Dintilhac A, Bernués J . HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences . The Journal of Biological Chemistry . 277 . 9 . 7021–8 . March 2002 . 11748221 . 10.1074/jbc.M108417200 . free . 10261/112516 . free .
• Dubois T, Howell S, Zemlickova E, Aitken A . Identification of casein kinase Ialpha interacting protein partners . FEBS Letters . 517 . 1–3 . 167–71 . April 2002 . 12062430 . 10.1016/S0014-5793(02)02614-5 . 84792445 . free . 2002FEBSL.517..167D .
• Bain M, Mendelson M, Sinclair J . Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells . The Journal of General Virology . 84 . Pt 1 . 41–9 . January 2003 . 12533699 . 10.1099/vir.0.18633-0 . free .
• Xiao X, Athanasiou M, Sidorov IA, Horikawa I, Cremona G, Blair D, Barret JC, Dimitrov DS . Role of Ets/Id proteins for telomerase regulation in human cancer cells . Experimental and Molecular Pathology . 75 . 3 . 238–47 . December 2003 . 14611815 . 10.1016/S0014-4800(03)00092-3 .
• Wolvetang EJ, Bradfield OM, Hatzistavrou T, Crack PJ, Busciglio J, Kola I, Hertzog PJ . Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis . Neurobiology of Disease . 14 . 3 . 349–56 . December 2003 . 14678752 . 10.1016/S0969-9961(03)00107-4 . 30142532 .
• Le Gallic L, Virgilio L, Cohen P, Biteau B, Mavrothalassitis G . ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression . Molecular and Cellular Biology . 24 . 3 . 1206–18 . February 2004 . 14729966 . 321421 . 10.1128/MCB.24.3.1206-1218.2004 .
• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP . A probability-based approach for high-throughput protein phosphorylation analysis and site localization . Nature Biotechnology . 24 . 10 . 1285–92 . October 2006 . 16964243 . 10.1038/nbt1240 . 14294292 .
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . November 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
• Hester KD, Verhelle D, Escoubet-Lozach L, Luna R, Rose DW, Glass CK . Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS . Cell Cycle . 6 . 13 . 1594–604 . July 2007 . 17525531 . 10.4161/cc.6.13.4336 . free .
• Verykokakis M, Papadaki C, Vorgia E, Le Gallic L, Mavrothalassitis G . The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression . The Journal of Biological Chemistry . 282 . 41 . 30285–94 . October 2007 . 17699159 . 10.1074/jbc.M704428200 . free .

Notes and References

1. Sgouras DN, Athanasiou MA, Beal GJ, Fisher RJ, Blair DG, Mavrothalassitis GJ . ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation . The EMBO Journal . 14 . 19 . 4781–93 . October 1995 . 7588608 . 394576 . 10.1002/j.1460-2075.1995.tb00160.x.
2. de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE . Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF) . Genomics . 42 . 2 . 227–35 . June 1997 . 9192842 . 10.1006/geno.1997.4730 .
3. Web site: Entrez Gene: ERF Ets2 repressor factor.