ERC2 (gene) explained

ERC protein 2 is a protein that in humans is encoded by the ERC2 gene.^[1]

Interactions

ERC2 (gene) has been shown to interact with PPFIA4,^[2] RIMS1,^{[3] [4]} UNC13A,^[5] and liprin-alpha-1.^[2]

Further reading

• Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T . Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones . DNA Research . 9 . 3 . 99–106 . June 2002 . 12168954 . 10.1093/dnares/9.3.99 . 10.1.1.500.923 .
• Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O . Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro . DNA Research . 4 . 2 . 141–50 . April 1997 . 9205841 . 10.1093/dnares/4.2.141 . free .
• Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y . Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1 . The Journal of Cell Biology . 158 . 3 . 577–90 . August 2002 . 12163476 . 2173811 . 10.1083/jcb.200202083 .
• Wang Y, Liu X, Biederer T, Südhof TC . A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones . Proceedings of the National Academy of Sciences of the United States of America . 99 . 22 . 14464–9 . October 2002 . 12391317 . 137906 . 10.1073/pnas.182532999 . 2002PNAS...9914464W . free .
• Ko J, Na M, Kim S, Lee JR, Kim E . Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins . The Journal of Biological Chemistry . 278 . 43 . 42377–85 . October 2003 . 12923177 . 10.1074/jbc.M307561200 . free .
• Deguchi-Tawarada M, Inoue E, Takao-Rikitsu E, Inoue M, Ohtsuka T, Takai Y . CAST2: identification and characterization of a protein structurally related to the presynaptic cytomatrix protein CAST . Genes to Cells . 9 . 1 . 15–23 . January 2004 . 14723704 . 10.1111/j.1356-9597.2004.00697.x . 13337267 . free .
• Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y . Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release . The Journal of Cell Biology . 164 . 2 . 301–11 . January 2004 . 14734538 . 2172332 . 10.1083/jcb.200307101 .
• tom Dieck S, Altrock WD, Kessels MM, Qualmann B, Regus H, Brauner D, Fejtová A, Bracko O, Gundelfinger ED, Brandstätter JH . Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex . The Journal of Cell Biology . 168 . 5 . 825–36 . February 2005 . 15728193 . 2171818 . 10.1083/jcb.200408157 .

Notes and References

1. Web site: Entrez Gene: ERC2 ELKS/RAB6-interacting/CAST family member 2.
2. Ko J, Na M, Kim S, Lee JR, Kim E . Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins . The Journal of Biological Chemistry . 278 . 43 . 42377–85 . October 2003 . 12923177 . 10.1074/jbc.M307561200 . free .
3. Takao-Rikitsu E, Mochida S, Inoue E, Deguchi-Tawarada M, Inoue M, Ohtsuka T, Takai Y . Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release . The Journal of Cell Biology . 164 . 2 . 301–11 . January 2004 . 14734538 . 2172332 . 10.1083/jcb.200307101 .
4. Ohtsuka T, Takao-Rikitsu E, Inoue E, Inoue M, Takeuchi M, Matsubara K, Deguchi-Tawarada M, Satoh K, Morimoto K, Nakanishi H, Takai Y . Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1 . The Journal of Cell Biology . 158 . 3 . 577–90 . August 2002 . 12163476 . 2173811 . 10.1083/jcb.200202083 .
5. Web site: Protein unc-13 homolog A. UniProt.