Enkurin Explained
Enkurin is a protein that in humans is encoded by the ENKUR gene.[1]
Enkurin interacts with transient receptor potential canonical (TRPC) cation channels (e.g., TRPC1) and functions as an adaptor protein, tethering signal transduction proteins to TRPC channels.[2]
Further reading
- Book: Beech DJ . Transient Receptor Potential (TRP) Channels . Canonical transient receptor potential . Handbook of Experimental Pharmacology . 179. 179 . 109–23 . 2007 . 17217053 . 10.1007/978-3-540-34891-7_6 . 978-3-540-34889-4 .
- Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 10.1073/pnas.242603899 . 139241. 2002PNAS...9916899M . etal. free .
- Deloukas P, Earthrowl ME, Grafham DV . The DNA sequence and comparative analysis of human chromosome 10. . Nature . 429 . 6990 . 375–81 . 2004 . 15164054 . 10.1038/nature02462 . 2004Natur.429..375D . etal. free .
- Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928. etal.
- Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
Notes and References
- Web site: Entrez Gene: enkurin.
- Sutton KA, Jungnickel MK, Wang Y, Cullen K, Lambert S, Florman HM . Enkurin is a novel calmodulin and TRPC channel binding protein in sperm . Dev. Biol. . 274 . 2 . 426–35 . October 2004 . 15385169 . 10.1016/j.ydbio.2004.07.031 .