EIF3M explained

Eukaryotic translation initiation factor 3, subunit M (eIF3m) also known as PCI domain containing 1 (herpesvirus entry mediator) (PCID1), is a protein that in humans is encoded by the EIF3M gene.^{[1] [2]}

HFLB5 encodes a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV).^{[1] [3]}

See also

• Eukaryotic initiation factor 3 (eIF3)

Further reading

• Kobayashi K, Xin Y, Ymer SI . Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells. . Brain Res. . 1170 . 129–39 . 2007. 17719568 . 10.1016/j.brainres.2007.07.042 . 31320196 . etal.
• Ewing RM, Chu P, Elisma F . Large-scale mapping of human protein-protein interactions by mass spectrometry. . Mol. Syst. Biol. . 3 . 1. 89 . 2007 . 17353931 . 10.1038/msb4100134 . 1847948 . etal.
• Perez-Romero P, Fuller AO . The C terminus of the B5 receptor for herpes simplex virus contains a functional region important for infection. . J. Virol. . 79 . 12 . 7431–7 . 2005 . 15919899 . 10.1128/JVI.79.12.7431-7437.2005 . 1143627 .
• Perez A, Li QX, Perez-Romero P . A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins. . J. Virol. . 79 . 12 . 7419–30 . 2005 . 15919898 . 10.1128/JVI.79.12.7419-7430.2005 . 1143644 . etal.
• Lehner B, Sanderson CM . A protein interaction framework for human mRNA degradation. . Genome Res. . 14 . 7 . 1315–23 . 2004 . 15231747 . 10.1101/gr.2122004 . 442147 .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 . etal.
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .

Notes and References

1. Web site: Entrez Gene: PCID1 PCI domain containing 1 (herpesvirus entry mediator).
2. Gawin B, Niederführ A, Schumacher N, Hummerich H, Little PF, Gessler M . A 7.5 Mb sequence-ready PAC contig and gene expression map of human chromosome 11p13-p14.1 . Genome Res. . 9 . 11 . 1074–86 . November 1999 . 10568747 . 310838 . 10.1101/gr.9.11.1074 .
3. Perez A, Li QX, Perez-Romero P, Delassus G, Lopez SR, Sutter S, McLaren N, Fuller AO . A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins . J. Virol. . 79 . 12 . 7419–30 . June 2005 . 15919898 . 1143644 . 10.1128/JVI.79.12.7419-7430.2005 .