EIF3J explained

Eukaryotic translation initiation factor 3 subunit J (eIF3j) is a protein that in humans is encoded by the EIF3J gene.^{[1] [2]}

Interactions

eIF3j has been shown to interact with eIF3a.^[3]

See also

• Eukaryotic initiation factor 3 (eIF3)

Further reading

• Asano K, Kinzy TG, Merrick WC, Hershey JW . Conservation and diversity of eukaryotic translation initiation factor eIF3 . J. Biol. Chem. . 272 . 2 . 1101–9 . 1997 . 8995409 . 10.1074/jbc.272.2.1101 . free .
• Méthot N, Rom E, Olsen H, Sonenberg N . The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170 . J. Biol. Chem. . 272 . 2 . 1110–6 . 1997 . 8995410 . 10.1074/jbc.272.2.1110 . free .
• Bushell M, Wood W, Clemens MJ, Morley SJ . Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis . Eur. J. Biochem. . 267 . 4 . 1083–91 . 2000 . 10672017 . 10.1046/j.1432-1327.2000.01101.x . free .
• Valásek L, Hasek J, Nielsen KH, Hinnebusch AG . Dual function of eIF3j/Hcr1p in processing 20 S pre-rRNA and translation initiation . J. Biol. Chem. . 276 . 46 . 43351–60 . 2001 . 11560931 . 10.1074/jbc.M106887200 . free .
• Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW . Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3 . Eur. J. Biochem. . 270 . 20 . 4133–9 . 2003 . 14519125 . 10.1046/j.1432-1033.2003.03807.x . free .
• Fraser CS, Lee JY, Mayeur GL, Bushell M, Doudna JA, Hershey JW . The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro . J. Biol. Chem. . 279 . 10 . 8946–56 . 2004 . 14688252 . 10.1074/jbc.M312745200 . free .
• Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP . A probability-based approach for high-throughput protein phosphorylation analysis and site localization . Nat. Biotechnol. . 24 . 10 . 1285–92 . 2006 . 16964243 . 10.1038/nbt1240 . 14294292 .
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . free .
• ElAntak L, Tzakos AG, Locker N, Lukavsky PJ . Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit . J. Biol. Chem. . 282 . 11 . 8165–74 . 2007 . 17190833 . 10.1074/jbc.M610860200 . free .

Notes and References

1. Block KL, Vornlocher HP, Hershey JW . Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3 . J. Biol. Chem. . 273 . 48 . 31901–8 . Dec 1998 . 9822659 . 10.1074/jbc.273.48.31901 . free .
2. Web site: Entrez Gene: EIF3S1 eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa.
3. Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW . Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3 . Eur. J. Biochem. . 270 . 20 . 4133–9 . Oct 2003 . 14519125 . 10.1046/j.1432-1033.2003.03807.x . free .