EID1 explained

EP300-interacting inhibitor of differentiation 1 is a protein that in humans is encoded by the EID1 gene.^{[1] [2] [3]}

Interactions

EID1 has been shown to interact with EP300^[4] and Retinoblastoma protein.^{[2] [4]}

Further reading

• Ghosh AK, Varga J . The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis. . J. Cell. Physiol. . 213 . 3 . 663–71 . 2007 . 17559085 . 10.1002/jcp.21162 . 41744258 . free .
• Margottin F, Bour SP, Durand H . A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif. . Mol. Cell . 1 . 4 . 565–74 . 1998 . 9660940 . 10.1016/S1097-2765(00)80056-8 . etal. free .
• Miyake S, Sellers WR, Safran M . Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle. . Mol. Cell. Biol. . 20 . 23 . 8889–902 . 2000 . 11073989 . 10.1128/MCB.20.23.8889-8902.2000 . 86544 . etal.
• Wen H, Ao S . Identification and characterization of a novel human cDNA encoding a 21 kDa pRb-associated protein. . Gene . 263 . 1–2 . 85–92 . 2001 . 11223246 . 10.1016/S0378-1119(00)00585-0 .
• Båvner A, Johansson L, Toresson G . A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP. . EMBO Rep. . 3 . 5 . 478–84 . 2002 . 11964378 . 10.1093/embo-reports/kvf087 . 1084100 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . etal. 2002PNAS...9916899M . free .
• Ledl A, Schmidt D, Müller S . Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor. . Oncogene . 24 . 23 . 3810–8 . 2005 . 15806172 . 10.1038/sj.onc.1208539 . free .
• Krützfeldt M, Ellis M, Weekes DB . Selective ablation of retinoblastoma protein function by the RET finger protein. . Mol. Cell . 18 . 2 . 213–24 . 2005 . 15837424 . 10.1016/j.molcel.2005.03.009 . etal. free .
• Benevolenskaya EV, Murray HL, Branton P . Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. . Mol. Cell . 18 . 6 . 623–35 . 2005 . 15949438 . 10.1016/j.molcel.2005.05.012 . etal. free .
• Rual JF, Venkatesan K, Hao T . Towards a proteome-scale map of the human protein-protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . etal. 2005Natur.437.1173R . 4427026 .

Notes and References

1. Carim L, Sumoy L, Andreu N, Estivill X, Escarceller M . Identification and expression analysis of C15orf3, a novel gene on chromosome 15q21.1→q21.2 . Cytogenet Cell Genet . 88 . 3–4 . 330–2 . June 2000 . 10828624 . 10.1159/000015523 . 27139235 .
2. MacLellan WR, Xiao G, Abdellatif M, Schneider MD . A novel Rb- and p300-binding protein inhibits transactivation by MyoD . Mol Cell Biol . 20 . 23 . 8903–15 . December 2000 . 11073990 . 86545 . 10.1128/MCB.20.23.8903-8915.2000 .
3. Web site: Entrez Gene: EID1 EP300 interacting inhibitor of differentiation 1.
4. 10.1128/MCB.20.23.8889-8902.2000 . Miyake . S . Sellers W R . Safran M . Li X . Zhao W . Grossman S R . Gan J . DeCaprio J A . Adams P D . Kaelin W G . December 2000 . Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle . Mol. Cell. Biol. . 20 . 23 . 8889–902 . 0270-7306. 11073989 . 86544 .