EAF2 explained
ELL-associated factor 2 is a protein that in humans is encoded by the EAF2 gene.[1] [2] [3] It is part of the EAF family of proteins.
Further reading
- Zhang QH, Ye M, Wu XY . Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells . Genome Res. . 10 . 10 . 1546–60 . 2001 . 11042152 . 10.1101/gr.140200 . 310934 . etal.
- Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
- Saso K, Ito T, Natori S, Sekimizu K . Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II . J. Biochem. . 133 . 4 . 493–500 . 2004 . 12761297 . 10.1093/jb/mvg065 .
- Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
- Kong SE, Banks CA, Shilatifard A . ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL . Proc. Natl. Acad. Sci. U.S.A. . 102 . 29 . 10094–8 . 2005 . 16006523 . 10.1073/pnas.0503017102 . 1177379 . 2005PNAS..10210094K . etal. free .
- Xiao W, Jiang F, Wang Z . ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation . Prostate . 66 . 1 . 1–12 . 2006 . 16114057 . 10.1002/pros.20309 . 32749490 .
- Jiang F, Ai J, Xiao W, Wang Z . FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity . Cancer Lett. . 253 . 2 . 265–72 . 2007 . 17395368 . 10.1016/j.canlet.2007.02.003 . 1989770 .
Notes and References
- Simone F, Luo RT, Polak PE, Kaberlein JJ, Thirman MJ . ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties . Blood . 101 . 6 . 2355–62 . Feb 2003 . 12446457 . 10.1182/blood-2002-06-1664 . free .
- Xiao W, Zhang Q, Jiang F, Pins M, Kozlowski JM, Wang Z . Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducer . Cancer Res . 63 . 15 . 4698–704 . Aug 2003 . 12907652 .
- Web site: Entrez Gene: EAF2 ELL associated factor 2.
