EAF1 explained

ELL-associated factor 1 is a protein that, in humans, is encoded by the EAF1 gene.^{[1] [2]} It is part of the EAF family of proteins.

Further reading

• Polak PE, Simone F, Kaberlein JJ, Luo RT, Thirman MJ . ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia . Molecular Biology of the Cell . 14 . 4 . 1517–28 . April 2003 . 12686606 . 153119 . 10.1091/mbc.E02-07-0394 .
• Kong SE, Banks CA, Shilatifard A, Conaway JW, Conaway RC . ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL . Proceedings of the National Academy of Sciences of the United States of America . 102 . 29 . 10094–8 . July 2005 . 16006523 . 1177379 . 10.1073/pnas.0503017102 . 2005PNAS..10210094K . free .
• Xiao W, Jiang F, Wang Z . ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation . The Prostate . 66 . 1 . 1–12 . January 2006 . 16114057 . 10.1002/pros.20309 . 32749490 .
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . November 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
• Jiang F, Ai J, Xiao W, Wang Z . FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity . Cancer Letters . 253 . 2 . 265–72 . August 2007 . 17395368 . 1989770 . 10.1016/j.canlet.2007.02.003 .

Notes and References

1. Simone F, Polak PE, Kaberlein JJ, Luo RT, Levitan DA, Thirman MJ . EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein . Blood . 98 . 1 . 201–9 . July 2001 . 11418481 . 10.1182/blood.V98.1.201 . 2577367 .
2. Web site: Entrez Gene: EAF1 ELL associated factor 1.