E. Dale Abel Explained
Evan Dale Abel (born 1963) is an American endocrinologist who serves as Chair of the Department of Medicine at the David Geffen School of Medicine at UCLA. His works on the molecular mechanisms that underpin cardiac failure in diabetes. He is a Fellow of the American Heart Association and the American College of Physicians. He was elected a member of the National Academy of Sciences in 2022.[1]
Early life and education
Abel is from Jamaica,[2] where he attended Wolmer's High School for Boys. He was encouraged by his parents to become a doctor, lawyer or engineer. He completed his undergraduate studies at the University of the West Indies, where he specialised in medicine. He completed his doctoral research in physiology at the University of Oxford. He was a medical intern in surgery and paediatrics at the University of the West Indies, before completing his residency in internal medicine at Northwestern University.[3]
Research and career
Abel started a clinical research fellowship in diabetes at Harvard Medical School in 1992.[4] He then joined the faculty at Harvard, where he was appointed co-Director of the fellowship programme at Beth Israel Deaconess Medical Center. He worked alongside Barbara Kahn, with whom who identified the relationship between adipose tissue glucose transporter (GLUT4) and insulin resistance. He was recruited to the faculty at the University of Utah in 2000, first as Assistant Professor and eventually as Professor of Medicine. Abel was supported by the National Institutes of Health to develop a mouse model of diabetes. He studied how glucose is delivered to cells.[5] He made use of conditional gene targeting to induce genetic defects that resulted in heart muscle cells being incapable of taking up glucose.
In 2013 Abel moved to the University of Iowa as Chair of the Department of Internal Medicine.[6] [7] His works on the molecular mechanisms that underpin cardiac failure in diabetes. He has investigated how diabetes impacts the formation of blood clots; with the increased glucose uptake of platelets in diabetic mice promoting overactivation and excess clotting.[8]
In 2022 Abel moved to the University of California, Los Angeles as Chair of the Department of Medicine in the David Geffen School of Medicine at UCLA.[9]
Awards and honors
Selected publications
- Boudina. Sihem. Abel. E. Dale. 2007-06-26. Diabetic Cardiomyopathy Revisited. Circulation. 115. 25. 3213–3223. 10.1161/circulationaha.106.679597. 17592090 . 0009-7322. free.
- Abel. E. Dale. Peroni. Odile. Kim. Jason K.. Kim. Young-Bum. Boss. Olivier. Hadro. Ed. Minnemann. Timo. Shulman. Gerald I.. Kahn. Barbara B.. 2001. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature. en. 409. 6821. 729–733. 10.1038/35055575. 11217863 . 4405220 . 1476-4687.
- Boudina. Sihem. Abel. Evan Dale. 2010. Diabetic cardiomyopathy, causes and effects. Reviews in Endocrine and Metabolic Disorders. en. 11. 1. 31–39. 10.1007/s11154-010-9131-7. 1389-9155. 2914514. 20180026.
Notes and References
- Web site: 2022 NAS Election .
- Web site: Member Spotlight: E. Dale Abel. 2021-01-03. www.im.org. en.
- Web site: E. Dale Abel Department of Internal Medicine. 2021-01-02. medicine.uiowa.edu.
- 2015-07-18. ENDOCRINE SOCIETY 2014 LAUREATE AWARDS. Endocrine Reviews. 10.1210/er.2014-1022.2016.1. 1945-7189. free.
- Web site: 2002-01-16. U's Young Scientist Unraveling Mystery Behind Heart Disease. 2021-01-03. The Daily Utah Chronicle.
- Web site: E. Dale Abel, MD, PhD. 2021-01-03. Making the Rounds. en-US.
- Web site: E. Dale Abel, MD, PhD Endocrine Society. 2021-01-03. www.endocrine.org.
- Web site: UI researchers study abnormal blood clotting in diabetes Carver College of Medicine. 2021-01-03. medicine.uiowa.edu.
- Web site: Endocrinologist Dr. E. Dale Abel appointed UCLA Department of Medicine chair UCLA Health. 2022-02-01. www.uclahealth.org.
- Web site: Evan Dale Abel, MBBS, DPhil - Faculty Details - U of U School of Medicine - University of Utah. 2021-01-02. medicine.utah.edu.
- Web site: 2016-03-23. Question and Answer with E. Dale Abel. 2021-01-02. Endocrine News. en-US.
- Web site: Biography E. Dale Abel Laboratory. 2021-01-02. abel.lab.uiowa.edu.
- Web site: Van Meter Award. 2021-01-02. American Thyroid Association. en-US.
- Web site: E. Dale Abel, MD, PhD Endocrine Society. 2021-01-02. www.endocrine.org.
- Web site: 2015-10-28. Five Black Scholars Elected to the National Academy of Medicine. 2021-01-03. The Journal of Blacks in Higher Education.
- Web site: NIH VideoCast - Sugar and the beating heart: the conundrum of heart failure in diabetes. 2021-01-02. videocast.nih.gov. 7 February 2018 .
- Web site: NIH Clinical Center: 2018 Astute Clinician Lecture. 2021-01-02. clinicalcenter.nih.gov.
- Web site: aldonovan97. 2018-10-03. Dr. Abel will receive a "History Makers Award" from the African American Museum of Iowa. 2021-01-02. Diabetes Center News Hub. en.
- Web site: Iowa. Internal Medicine at. 2020-03-04. Abel named APM president-elect. 2021-01-02. Making the Rounds. en-US.
- Web site: Scholars. The Community of. 1,000 inspiring Black scientists in America. 2021-01-02. crosstalk.cell.com. en-us.