| Eşen | |
| Name Other: | Seki Çayı |
| Subdivision Type1: | Country |
| Subdivision Name1: | Turkey |
| Subdivision Type3: | Provinces |
| Subdivision Name3: | Antalya, Burdur, Muğla |
| Subdivision Type4: | Districts (ilçe) |
| Subdivision Name4: | Korkuteli, Seydikemer, Altınyayla, Fethiye, Kaş |
| Length: | 120km (80miles) |
| Source1: | At the west side of Kızılca Dağ, Taurus Mountains |
| Source1 Elevation: | 2000 m |
| Mouth: | Mediterranean Sea |
| Mouth Location: | Border between Muğla Province and Antalya Province |
| Mouth Coordinates: | 36.2935°N 29.2625°W |
| Mouth Elevation: | 0 m |
| Tributaries Left: | Karaçay |
| Tributaries Right: | Akçay |
Eşen River (Turkish: Eşen çeyı or Seki Çayı) is a river in south west Turkey. - river flows mostly in Muğla Province. It flows in the middle of Seydikemer ilçe (district) of Muğla Province.[1] The river although quite short is known for its touristic importance.
In the antiquity the river as well as the ancient city by the river was known as Xanthos. Both Patara and Letoon are nearby. Currently visitors enjoy rafting in the lower course of the river which draws the border line between Muğla and Antalya Provinces.[2]