Dyschromatosis universalis hereditaria explained

Dyschromatosis universalis hereditaria
Field:	Dermatology

Dyschromatosis universalis hereditaria is a type of pigmentation disorder of the skin.^[1] It is characterized by dark and light spots formed like lace in a generalized distribution.^[1]

Both autosomal dominant and recessive inheritance have been reported with the disorder.^[2]

It has been associated with mutations in genes SASH1 and ABCB6.

It is a rare genodermatosis.^[1]

Notes and References

1. Book: James . William D. . Elston . Dirk . Treat . James R. . Rosenbach . Misha A. . Neuhaus . Isaac . Andrews' Diseases of the Skin: Clinical Dermatology . 2020 . Elsevier . Edinburgh . 978-0-323-54753-6 . 865–866 . 13th . https://books.google.com/books?id=UEaEDwAAQBAJ&pg=PA865 . en . 36. Disturbances of pigmentation .
2. 18462451 . June 2008 . Stuhrmann M, Hennies HC, Bukhari IA, Brakensiek K, Nürnberg G, Becker C, Huebener J, Miranda MC, Frye-Boukhriss H, Knothe S, Schmidtke J, El-Harith EH . Dyschromatosis universalis hereditaria: evidence for autosomal recessive inheritance and identification of a new locus on chromosome 12q21-q23 . 73 . 6 . 566–572 . 10.1111/j.1399-0004.2008.01000.x . Clinical Genetics . 9623609 .