| Duplin River | |
| Pushpin Map: | Georgia (U.S. state) |
| Pushpin Map Caption: | Location of mouth |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Georgia |
The Duplin River is an 8.1adj=midNaNadj=mid[1] tidal river in McIntosh County, Georgia, in the United States. It flows from north to south along the western edge of Sapelo Island into Doboy Sound, an arm of the Atlantic Ocean.[2]