| Dumisani Matyeshana | |
| Birth Date: | 11 February 1981 |
| Birth Place: | Mdantsane, East London, South Africa |
| Weight: | 920NaN0 |
| School: | Selborne College |
| University: | Border Tech |
| Position: | Winger / Centre |
| Currentclub: | Rustenburg Impala |
| Youthyears1: | 2002 |
| Youthyears2: | 2003 |
| Years1: | 2004–2006 |
| Apps1: | 31 |
| Points1: | 55 |
| Years2: | 2007 |
| Apps2: | 8 |
| Points2: | 25 |
| Years3: | 2007–2008 |
| Apps3: | 5 |
| Points3: | 7 |
| Years4: | 2009 |
| Apps4: | 13 |
| Points4: | 5 |
| Years5: | 2010–11, 2013–present |
| Apps5: | 26 |
| Points5: | 50 |
| Years6: | 2013 |
| Apps6: | 2 |
| Points6: | 0 |
| Amatyears1: | 2014–present |
| Amatteam1: | Rustenburg Impala |
| Amatapps1: | 14 |
| Amatpoints1: | 25 |
| Clubupdate: | 7 April 2015 |
Dumisani Matyeshana (born 11 February 1981 in East London) is a South African rugby union player for club side Rustenburg Impala. He plays as a winger, centre or full-back and previously played provincial rugby for the, and .