| Duilio Santagostino | |
| Birth Date: | 15 April 1914 |
| Birth Place: | Turin, Italy |
| Death Place: | Turin, Italy |
| Position: | Midfielder |
| Years1: | 1932–1933 |
| Years2: | 1933–1934 |
| Years3: | 1934–1937 |
| Years4: | 1937–1940 |
| Years5: | 1940–1942 |
| Years6: | 1942–1943 |
| Clubs2: | Juventus (B team) |
| Clubs3: | Juventus |
| Clubs5: | Savigliano |
| Clubs6: | Settimese |
| Caps1: | 1 |
| Caps3: | 0 |
| Caps4: | 55 |
| Goals1: | 0 |
| Goals3: | 0 |
| Goals4: | 0 |
Duilio Santagostino (April 15, 1914 in Turin – October 6, 1982 in Turin), was an Italian professional football player.