| Duesme | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason de la ville de Duesme (Côte-d'Or).svg |
| Arrondissement: | Montbard |
| Canton: | Châtillon-sur-Seine |
| Insee: | 21235 |
| Postal Code: | 21510 |
| Mayor: | Bernard Mongenet[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Pays Châtillonnais |
| Coordinates: | 47.6439°N 4.6844°W |
| Elevation M: | 308 |
| Elevation Min M: | 303 |
| Elevation Max M: | 424 |
| Area Km2: | 13.33 |
Duesme (in French pronounced as /dɥɛm/) is a commune in the Côte-d'Or department in eastern France.