| Dryden Brook | |
| Pushpin Map: | New York |
| Pushpin Map Caption: | Location of the mouth of Dryden Brook |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Delaware |
| Source1 Coordinates: | 42.1809°N -75.2068°W |
| Mouth: | Cannonsville Reservoir |
| Mouth Coordinates: | 42.1101°N -75.2616°W[1] |
| Mouth Elevation: | 1148feet |
Dryden Brook is a river in Delaware County, New York. It flows into Cannonsville Reservoir west-northwest of Rock Rift.