Dronabinol/acetazolamide explained

Synonyms:	IHL-42X
Type:	combo
Component1:	Dronabinol
Class1:	Cannabinoid
Component2:	Acetazolamide
Class2:	Carbonic anhydrase inhibitor
Legal Status:	Investigational

Dronabinol/acetazolamide (investigational name IHL-42X) is a combination therapy under investigation for sleep apnea. It is developed by Incannex Healthcare.^{[1] [2]}

Notes and References

1. Walsh . J . Rankin . T . Mehra . S . Naughton . M . Roebuck . T . McDermott . E . Pattichis . A . Smith . R . Germaine . J . Walsh . R . Bleackley . M . Maddison . K . O'Brien . T . O027 A randomised dose finding study of combination dronabinol and acetazolamide for the treatment of obstructive sleep apnoea: A proof of concept study . Sleep Advances: A Journal of the Sleep Research Society . 9 November 2022 . 3 . Suppl 1 . A11 . 10.1093/sleepadvances/zpac029.026 . 10109426 . 2632-5012.
2. Thomson . Luke . Rankin . Timothy . Mehra . Sumit . Naughton . Matthew . Roebuck . Teanau . McDermott . Elizabeth . Pattichis . Andreas . Smith . Rafael . Germaine . Jack . Walsh . Rosemarie . Bleackley . Mark . Edwards . Bradley . Maddison . Kathleen . O'Brien . Terence . Walsh . Jen . 0451 Dronabinol Plus Acetazolamide for the Treatment of Obstructive Sleep Apnoea: A Proof of Concept and Mechanistic Exploration Study . SLEEP . 29 May 2023 . 46 . Supplement_1 . A200–A201 . 10.1093/sleep/zsad077.0451. free .