Drew Endy Explained

Fields:Synthetic biology
Workplaces:Stanford University
Massachusetts Institute of Technology
Dartmouth College
Alma Mater:Dartmouth College
Thesis Title:Development and application of a genetically-structured simulation for bacteriophage T7
Thesis Url:http://search.proquest.com/docview/304348966
Thesis Year:1997
Doctoral Advisor:John Yin[1]
Website:
Spouse:Christina Smolke[2]

Andrew (Drew) David Endy (born 1970) is a synthetic biologist and tenured associate professor of bioengineering at Stanford University, California.[3] [4] [5] [6] [7]

Education

Endy received his PhD from Dartmouth College in 1997 for his work on genetic engineering using T7 phage.[8]

Career

Endy was a junior fellow for three years and later an Assistant Professor of Biological Engineering at the Massachusetts Institute of Technology (2002–2008). In 2008, Endy moved to Stanford University, where he currently serves as an Associate Professor of Bioengineering.[9] [10]

Research

With Thomas Knight,[11] Gerald Jay Sussman, Randy Rettberg, and others at MIT, Endy worked on synthetic biology and the engineering of standardized biological components, devices, and parts, collectively known as BioBricks.[12] Endy is one of several founders of the Registry of Standard Biological Parts, and invented an abstraction hierarchy for integrated genetic systems.

Endy has been one of the early promoters of open source biology,[13] and helped start the Biobricks Foundation, a not-for-profit organization that will work to support open-source biology. He was also a co-founder of the now defunct Codon Devices, a biotechnology startup company that aimed to commercialize synthetic biology.[14]

In 2009, Michael Specter called Endy "synthetic biology’s most compelling evangelist" in his book Denialism: How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives,[15] as Endy is persistent in discussing both the prospects and dangers of synthetic biology.

Endy headed a team of researchers that in March 2013 created the biological equivalent of a transistor, which they dubbed a "transcriptor". The invention was the final of the three components necessary to build a fully functional biocomputer: data storage, information transmission, and a basic system of logic.[16]

Endy is a founder and steering group member of the Build-a-Cell Initiative, an international collaboration investigating creation of synthetic live cells.[17]

External links

Notes and References

  1. Endy . D. . Kong . D. . Yin . J. . 10.1002/(SICI)1097-0290(19970720)55:2<375::AID-BIT15>3.0.CO;2-G . Intracellular kinetics of a growing virus: A genetically structured simulation for bacteriophage T7 . Biotechnology and Bioengineering . 55 . 2 . 375–389 . 1997 . 18636496 .
  2. 365 days: Nature's 10 . 10.1038/528459a. 26701036 . Nature . 528. 7583. 459–467. 2015. 2015Natur.528..459.. free.
  3. Endy . D. . Foundations for engineering biology . 10.1038/nature04342 . Nature . 438 . 7067 . 449–453 . 2005 . 16306983 . 2005Natur.438..449E . 1436520 .
  4. Colman-Lerner . A. . Gordon . A. . Serra . E. . Chin . T. . Resnekov . O. . Endy . D. . Gustavo Pesce . C. . Brent . R. . 10.1038/nature03998 . Regulated cell-to-cell variation in a cell-fate decision system . Nature . 437 . 7059 . 699–706 . 2005 . 16170311 . 2005Natur.437..699C . 4398874 .
  5. Endy . D. . Yaffe . M. B. . 10.1038/426614a . Signal transduction: Molecular monogamy . Nature . 426 . 6967 . 614–615 . 2003 . 14668845 . 2003Natur.426..614E . free .
  6. Endy . D. . Brent . R. . Modelling cellular behaviour . Nature . 409 . 6818 . 391–395 . 10.1038/35053181 . 2001 . 11201753 . 2001Natur.409..391E . free .
  7. Canton . B. . Labno . A. . Endy . D. . 10.1038/nbt1413 . Refinement and standardization of synthetic biological parts and devices . Nature Biotechnology . 26 . 7 . 787–793 . 2008 . 18612302. 19797363 .
  8. PhD . Andrew David. Endy . Development and application of a genetically-structured simulation for bacteriophage T7 . Dartmouth College . 1997 . Drew Endy. .
  9. Web site: Stanford Engineering: Drew Endy . Stanford.edu . 1 December 2021.
  10. Web site: Platoni . Kara . Assembly Required . Stanfordmag.org . 16 December 2011 . Stanford Magazine . 1 December 2021.
  11. Shetty . R. P. . Endy . D. . Knight . T. F. . Engineering BioBrick vectors from BioBrick parts . 10.1186/1754-1611-2-5 . Journal of Biological Engineering . 2 . 5 . 2008 . 18410688 . 2373286 . free .
  12. https://www.theguardian.com/science/2005/mar/10/science.research From the cells up
  13. News: Lohr . Steve . Can Synthetic Biology Save Us? This Scientist Thinks So. . 1 December 2021 . New York Times . November 23, 2021.
  14. News: Check Hayden . Erika . Ledford . Heidi . A synthetic-biology reality check . 1 December 2021 . Nature . 458 . April 16, 2009.
  15. Book: Specter, Michael. Michael Specter. Denialsim How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives. 2009. Penguin Group. 978-1-59420-230-8. 242–253. registration.
  16. News: This new discovery will finally allow us to build biological computers. Robert T. Gonzalez. IO9. March 29, 2013. March 29, 2013.
  17. Web site: Build-a-Cell. 4 Dec 2020.

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