| Official Name: | Drenkovo |
| Native Name: | Дренково |
| Settlement Type: | Village |
| Pushpin Map: | Bulgaria |
| Pushpin Label Position: | Location in Bulgaria |
| Subdivision Name: |  Bulgaria |
| Subdivision Type1: | Province |
| Subdivision Name1: | Blagoevgrad Province |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Blagoevgrad |
| Leader Title: | Suffragan Mayor |
| Leader Name: | Kiril Ivanovski |
| Area Total Km2: | 24.517 |
| Population As Of: | 15 December 2010[1] |
| Population Note: | GRAO |
| Population Total: | 62 |
| Timezone: | EET |
| Utc Offset: | +2 |
| Timezone Dst: | EEST |
| Utc Offset Dst: | +3 |
| Postal Code Type: | Postal Code |
| Postal Code: | 2739 |
| Area Code: | 07413 |
| Coordinates: | 42.0167°N 77°W |
| Elevation M: | 832 |
Drenkovo is a sparsely populated and dispersed village in Blagoevgrad Municipality, in Blagoevgrad Province, Bulgaria. It is situated in the foothills of Vlahina mountain few kilometers west of Blagoevgrad and north from the road to North Macedonia. There are ruins of Roman villa near the village.