| Consort: | yes |
| Dorothea Maria of Saxe-Weimar | |
| Succession: | Duchess consort of Saxe-Zeitz |
| Reign: | 1657–1675 |
| House: | Wettin |
| Father: | William, Duke of Saxe-Weimar |
| Mother: | Eleonore Dorothea of Anhalt-Dessau |
| Spouse: | Maurice, Duke of Saxe-Zeitz |
| Issue-Link: |
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| Birth Place: | Weimar |
| Death Place: | Moritzburg Palace in Zeitz |
Dorothea Maria of Saxe-Weimar (14 October 1641 – 11 June 1675), was by birth Duchess of Saxe-Weimar from the Ernestine branch of the House of Wettin and by marriage Duchess of Saxe-Zeitz.
Born in Weimar, Dorothea Maria was the youngest daughter of Duke William IV of Saxe-Weimar from his marriage to Eleonore Dorothea of Anhalt-Dessau, the daughter of Prince John George I of Anhalt-Dessau. She was named after her maternal grandmother Dorothea Maria of Anhalt, who had already died at that point in time.
Her marriage to Duke Maurice of Saxe-Zeitz can be understood against the background of the fact that Maurice had been administrator of the Bishopric of Naumburg-Zeitz since 1653 and lived in City Palace in Naumburg. Furthermore, Maurice had been a member since 1646, of the Fruitbearing Society, led by Dorothea Maria's father.
Maurice had been married before and had been a widower since 7 October 1652. When the customary mourning period had ended, he married Dorothea Maria, who was only 15 years old. Maurice's father, Elector John George I of Saxony died. Maurice inherited the Lordship of Zeitz as an apanage, making him the founder of the Saxe-Zeitz branch of the House of Wettin.
Maurice held that the City Palace in Naumburg was not a befitting residence for a person of his station and summoned his father court architect, Johann Moritz Richter, to discuss the design of a magnificent baroque palace, Moritzburg Palace, in his new capital Zeitz.
The Duke and Duchess saw as their main task to revive the economy and to repair the devastation of the infrastructure of their principality during the Thirty Years' War. They also devoted themselves to the reconstruction of the seminary in Zeitz. Christoph Cellarius would later add great prestige to this seminary.
Dorothea Maria died in the Moritzburg Palace, Zeitz on 11 June 1675, at the age of 33. She was buried in a magnificent sarcophagus in the hall crypt below the Cathedral of St. Peter and Paul in Zeitz. Her husband remarried after her death. This third marriage, however, remained childless, so that the Saxe-Zeitz line descends from Dorothea Maria. However, the line died out after the third generation, due to lack of male heirs.
She married on 3 July 1656 in Weimar with Duke Maurice of Saxe-Zeitz, the youngest surviving son of Elector John George I of Saxony, from his second marriage, with Duchess Magdalene Sibylle of Prussia. They had ten children:
