| Dondon Ampalayo | |
| Number: | 6, 54 |
| Nationality: | Filipino |
| Birth Date: | 18 April 1963 |
| Birth Place: | Cebu City, Philippines |
| Height Ft: | 6 |
| Height In: | 3 |
| Weight Lbs: | 190 |
| College: | USJ–R |
| Draft Year Pba: | 1986 |
| Draft Round Pba: | 1 |
| Draft Pick Pba: | 3 |
| Draft Team Pba: | Ginebra San Miguel |
| Career Start: | 1986 |
| Career End: | 1995 |
| Career Position: | Power forward |
| Years1: | 1986–1993 |
| Team1: | Ginebra San Miguel / Añejo Rum 65 |
| Years2: | 1993–1995 |
| Team2: | Alaska Milkmen |
| Awards: | |
Cresencio "Dondon" Ampalayo (born April 18, 1963 in Cebu City, Philippines) is a Filipino retired professional basketball player in the Philippine Basketball Association.
Dubbed as the 'Magician' or the 'Magic Man' in the PBA, Ampalayo won Rookie of the Year honors in 1986 while suiting up for Ginebra San Miguel. Before turning pro, Ampalayo saw action for ESQ Merchants in the PABL.[1] Known for his pivot moves underneath the basket as well as adept three-point shooting, Dondon won three championships in eight seasons with Ginebra from 1986 to 1993. A mid-season trade in 1993 saw Ampalayo's transfer to the Alaska Milkmen in exchange for Bobby Jose. He played two more seasons with Alaska before persistent knee problems finally took its toll on him and cut short his career.
Dondon is now living in the United States with his wife Anne Pasco Ampalayo, and sons Aldreen and Zachary.