Donald Engelman Explained

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Donald Max Engelman
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Module:	Birth Date: 1941 Embed: yes Fields: Cancer drugs and treatments Thesis Title: Solubilization and Aggregation Properties of Membrane Components from Mycoplasma laidlawii Thesis Url: http://search.proquest.com/docview/302391675 Thesis Year: 1968 Doctoral Students: Mark A. Lemmon^[1] ^[2]

Donald Max Engelman (born 1941) is Higgins Professor of Biochemistry at Yale University. He is a member of the National Academy of Sciences (1997), fellow of the American Academy of Arts and Sciences,^[3] a fellow of the National Institutes of Health, and has been a Guggenheim fellow.^[4] He served as the editor of the Annual Review of Biophysics and Biophysical Chemistry (1984–1993).^[5]

He is a director of the Stryker Corporation.^[6] He is involved in the creation of new cancer drugs and treatments.^[7] For example, Engelman is involved in research to use peptides to aid in destroying tumors.^[8]

Administration, advising, and consulting

Engelman has served as Director of Biological Sciences at Yale, an advisor to the Brookhaven National Laboratory, and a consultant to the Los Alamos National Laboratory.^[9] He also served as Acting Dean of Yale College in 1991.^[10]

Education

Engelman is a graduate (and trustee^[11]) of Reed College receiving his degree in physics. He then earned his Ph.D. in molecular biophysics at Yale University in 1969.^{[12] [13]}

Engelman Lab

Engelman directs the Engelman Laboratory at Yale focused on the biophysics of biological membranes. His group is best known for elucidating the mechanism of pH Low Insertion Peptide (pHLIP) to form trans-membrane helices.^[14]

Patents

Engelman holds six United States patents for his discoveries.^[15]

Notes and References

1. Lemmon. Mark A.. Flanagan. John M.. Treutlein. Herbert R.. Zhang. Jian. Engelman. Donald M.. Sequence specificity in the dimerization of transmembrane .alpha.-helixes. Biochemistry. 31. 51. 1992. 12719–12725. 1463743. 10.1021/bi00166a002.
2. PhD . Mark Andrew. Lemmon . Specific interactions between transmembrane alpha-helices: Their role in the oligomerization of integral membrane proteins . Yale University . 1993 . .
3. Web site: REED COLLEGE AMERICAN ACADEMY OF ARTS AND SCIENCES AWARDS.
4. Web site: All Fellows - John Simon Guggenheim Memorial Foundation . Gf.org . 2011-07-06 . dead . https://web.archive.org/web/20110628225548/http://www.gf.org/fellows/all?index=e&page=5 . 2011-06-28 .
5. Web site: Engelman and de la Huerga join the board of trustees. Reed Magazine. August 2000. 17 December 2020.
6. News: Donald M. Engelman Profile - Forbes.com . People.forbes.com . 2011-07-06.
7. Web site: URI Research Couple's Method Targets Cancerous Tumors - Redorbit. redOrbit. Redorbit. 27 October 2009.
8. Web site: Home.
9. Web site: Reed Magazine: News of the College.
10. News: A Yale College Dean Is Named . The New York Times . 1991-10-15.
11. Web site: List of Public Companies Worldwide, Letter - Businessweek - Businessweek. Businessweek.com.
12. Web site: The Engelman Lab - Donald M. Engelman . Yale.edu . 2011-07-06 . https://web.archive.org/web/20120110143920/http://www.yale.edu/engelman/DME.html . 2012-01-10 . dead .
13. News: Roy . Yash . am . Giri Viswanathan 12:37 . Two Yale faculty members elected as fellows of the American Association for the Advancement of Science . Yale Daily News . 2 February 2022 . en.
14. Reshetnyak . Yana K. . Andreev . Oleg A. . Segala . Michael . Markin . Vladislav S. . Engelman . Donald M. . Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane . Proceedings of the National Academy of Sciences . 7 October 2008 . 105 . 40 . 15340–15345 . 10.1073/pnas.0804746105. 18829441 . 2556629 . 2008PNAS..10515340R . free .
15. Web site: Donald M Engelman, Page 1.