| Domingos Lopes | |
| Fullname: | Domingos António Lopes |
| Birth Date: | 23 August 1912 |
| Birth Place: | Mina de São Domingos, Portugal |
| Death Date: | Deceased |
| Position: | Midfielder |
| Youthyears1: | 1927–1929 |
| Youthclubs1: | Lusitano VRSA |
| Years1: | 1929–1933 |
| Years2: | 1933–1938 |
| Years3: | 1938–1939 |
| Clubs3: | Lusitano VRSA |
| Nationalyears1: | 1934 |
| Nationalteam1: | Portugal |
| Nationalcaps1: | 2 |
| Nationalgoals1: | 0 |
Domingos António Lopes (born 23 August 1912, date of death unknown) was a Portuguese footballer who played as forward. He was born in Mina de São Domingos.