| Honorific-Prefix: | Most Reverend |
| Domingo de Alzola | |
| Bishop of Guadalajara | |
| Church: | Catholic Church |
| Diocese: | Diocese of Guadalajara |
| Term: | 1582–1590 |
| Predecessor: | Francisco Gómez de Mendiola y Solórzano |
| Successor: | Pedro Suarez de Escobar |
| Consecration: | October 19, 1582 |
| Birth Date: | 1532 |
| Birth Place: | Mondragón, Spain |
| Death Date: | February 15, 1590 (age 58) |
| Death Place: | Guadalajara, Mexico |
| Nationality: | Spanish |
Domingo de Alzola (1532 – February 15, 1590) was a Roman Catholic prelate who served as Bishop of Guadalajara (1582–1590).[1] [2]
Domingo de Alzola was born in Mondragón, Spain and ordained a priest in the Order of Preachers. On October 1, 1582, he was appointed by the King of Spain and confirmed by Pope Gregory XIII as Bishop of Guadalajara. On October 19, 1582, he was consecrated bishop. In 1585, he attended the Third Mexican Provincial Council.[3]
He served as Bishop of Guadalajara until his death on February 15, 1590.