| Official Name: | Domingo Martínez de Irala |
| Settlement Type: | District |
| Pushpin Map: | Paraguay |
| Mapsize: | 200px |
| Subdivision Type: | Country |
| Subdivision Name: | Paraguay |
| Subdivision Type1: | Department |
| Leader Name: | Derlis Javier Benegas Carrera |
| Established Title: | Foundation |
| Established Date: | 7 July 1896 |
| Area Total Km2: | 334 |
| Population As Of: | 2017 |
| Population Total: | 5,956 |
| Population Footnotes: | [1] |
| Timezone: | -4 Gmt |
| Coordinates: | -25.9381°N -54.7247°W |
| Elevation M: | 249 |
| Postal Code Type: | Postal code |
| Postal Code: | 7700 |
| Area Code: | (595) (678) |
Domingo Martínez de Irala is a district located in the Alto Paraná Department of Paraguay.