| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Domenico de' Dominichi | |
| Bishop of Brescia | |
| Church: | Catholic Church |
| Diocese: | Diocese of Brescia |
| Term: | 1464–1478 |
| Successor: | Lorenzo Zanni |
| Death Date: | 1478 |
| Previous Post: | Bishop of Torcello (1448–1464) |
Domenico de' Domenichi or Domenico de Dominicis (died 1478) was a Roman Catholic prelate who served as Bishop of Brescia (1464–1478)[1] and Bishop of Torcello (1448–1464).[2]
On 20 February 1448, Domenico de Dominicis was appointed during the papacy of Pope Nicholas V as Bishop of Torcello.[3] On 14 November 1464, he was appointed during the papacy of Pope Paul II as Bishop of Brescia.He served as Bishop of Brescia until his death in 1478. While bishop, he was the principal consecrator of Johannes Hinderbach, Bishop of Trento (1466); and the principal co-consecrator of Giovanni Stefano Botticelli, Bishop of Cremona (1467).