| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Domenico Maria Marchese | |
| Bishop of Pozzuoli | |
| Church: | Catholic Church |
| Diocese: | Diocese of Pozzuoli |
| Term: | 1688–1692 |
| Predecessor: | Diego Ibáñez de la Madrid y Bustamente |
| Successor: | José Sanz de Villaragut |
| Consecration: | 8 Jun 1688 |
| Consecrated By: | Galeazzo Marescotti |
| Birth Date: | 2 Mar 1633 |
| Death Date: | May 1692 (age 59) |
Domenico Maria Marchese, O.P. (1633–1692) was a Roman Catholic prelate who served as Bishop of Pozzuoli (1688–1692).
Domenico Maria Marchese was born on 2 Mar 1633 in Naples, Italy and ordained a priest in the Order of Preachers.
On 31 May 1688, he was appointed Bishop of Pozzuoli by Pope Innocent XI.On 31 May 1688, he was consecrated bishop by Galeazzo Marescotti, Cardinal-Priest of Santi Quirico e Giulitta, with Pietro de Torres, Archbishop of Dubrovnik, and Pier Antonio Capobianco, Bishop Emeritus of Lacedonia, serving as co-consecrators.
He served as Bishop of Pozzuoli until his death in May 1692.