Dolichylphosphate-glucose phosphodiesterase explained

dolichylphosphate-glucose phosphodiesterase
Ec Number:	3.1.4.48
Cas Number:	89287-42-3
Go Code:	0047397

The enzyme dolichylphosphate-glucose phosphodiesterase (EC 3.1.4.48)^[1] catalyzes the reaction

dolichyl β-D-glucosyl phosphate + H₂O

\rightleftharpoons dolichyl phosphate + D-glucose

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is dolichyl-β-D-glucosyl-phosphate dolichylphosphohydrolase. Other names in common use include dolichol phosphoglucose phosphodiesterase, and Dol-P-Glc phosphodiesterase. This enzyme participates in n-glycan biosynthesis.

Notes and References

1. Crean EV . 1984 . Synthesis and degradation of dolichyl phosphoryl glucose by the cellular slime mold, Dictyostelium discoideum . Biochim. Biophys. Acta . 792 . 149 - 157 . 10.1016/0005-2760(84)90216-9.