Docking protein 6 explained

Docking protein 6 is a protein that in humans is encoded by the DOK6 gene.^[1]

Function

DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).

Further reading

• Crowder RJ, Enomoto H, Yang M, Johnson EM, Milbrandt J . Dok-6, a Novel p62 Dok family member, promotes Ret-mediated neurite outgrowth . J. Biol. Chem. . 279 . 40 . 42072–81 . 2004 . 15286081 . 10.1074/jbc.M403726200 . free.
• Kurotsuchi A, Murakumo Y, Jijiwa M, Kurokawa K, Itoh Y, Kodama Y, Kato T, Enomoto A, Asai N, Terasaki H, Takahashi M . Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells . Cancer Sci. . 101 . 5 . 1147–55 . 2010 . 20210798 . 10.1111/j.1349-7006.2010.01520.x . 11769638 . free . 11159970 .

Notes and References

1. Web site: Entrez Gene: Docking protein 6. 2017-02-01.