| Do Peixe River | |
| Source1 Location: | Santa Catarina state |
| Mouth: | Uruguay River |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
| Length: | 249km (155miles)[1] |
| Source1 Elevation: | 1250m (4,100feet) |
| Mouth Elevation: | 387m (1,270feet) |
| Basin Size: | 5277km2 |
The Do Peixe River is a river of Santa Catarina state in southeastern Brazil. It is part of the Uruguay River basin.