The Dnipropetrovsk Regional Committee of the Communist Party of Ukraine, commonly referred to as the Dnipropetrovsk CPU obkom, was the position of highest authority in the Dnipropetrovsk Oblast, in the Ukrainian SSR of the Soviet Union. The position was created on February 27, 1932, and abolished in August 1991. The First Secretary was a de facto appointed position usually by the Central Committee of the Communist Party of Ukraine or the First Secretary of the Republic.
| Name | Term of office | Life years | ||
|---|---|---|---|---|
| Start | End | |||
| First Secretaries of the Oblast Committee of the Communist Party | ||||
| Vladimir Chernyavskiy | February 1932 | October 1932 | 1893–1939 | |
| Vasyliy Stroganov | October 1932 | January 1933 | 1888–1938 | |
| Mendel Khatayevich | January 1933 | March 1937 | 1893–1939 | |
| Natan Margolin | March 1937 | November 1937 | 1895–1938 | |
| Demyan Korotchenko | November 1937 | February 24, 1938 | 1894–1969 | |
| Semen Zadionchenko (Zayonchik) | February 24, 1938 | July 1941 | 1898–1972 | |
| Konstantin Grushevy | July 1941 | October 1941 | 1906–1982 | |
| Nazi German occupation (1941–1943) | ||||
| Georgiy Dementyev | 1943 | February 1944 | ||
| Pavel Naydenov | February 1944 | November 1947 | 1905–1967 | |
| Leonid Brezhnev | November 27, 1947 | June 1950 | 1906–1982 | |
| Andrei Kirilenko | June 1950 | December 1955 | 1906–1990 | |
| Vladimir Shcherbitskiy | December 1955 | December 1957 | 1918–1990 | |
| Anton Gayevoi | December 1957 | May 1961 | 1907–1962 | |
| Nikita Tolubeyev | May 1961 | July 7, 1963 | 1922– | |
| Aleksei Vatchenko | January 1963 | December 1964 | 1914–1984 | |
| Vladimir Shcherbitskiy | July 7, 1963 | October 1965 | 1918–1990 | |
| Aleksei Vatchenko | October 1965 | June 1976 | 1914–1984 | |
| Yevgeniy Kachalovskiy | June 1976 | 1983 | 1926–2011 | |
| Viktor Boyko | 1983 | April 20, 1987 | 1931– | |
| Vladimir Ivashko | April 20, 1987 | December 14, 1988 | 1932–1994 | |
| Nikolai Zadoya | December 14, 1988 | August 31, 1990 | 1938– | |
| Nikolai Omelchenko | August 31, 1990 | August 1991 | 1936– | |