DnaX ribosomal frameshifting element explained

DnaX ribosomal frameshifting element
Symbol:DnaX
Rfam:RF00382
Rna Type:Cis-reg
frameshift_element
Tax Domain:Bacteria

The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two encoded products, tau and gamma, which are produced in a 1:1 ratio. The gamma protein is synthesised due to programmed frameshifting and is shorter than tau. The two products of the dnaX gene are DNA polymerase III subunits.[1] [2]

Notes and References

  1. Larsen B, Gesteland RF, Atkins JF . Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: programmed efficiency of 50% . Journal of Molecular Biology . 271 . 1 . 47–60 . August 1997 . 9300054 . 10.1006/jmbi.1997.1162 . 7126992 .
  2. Blinkova A, Burkart MF, Owens TD, Walker JR . Conservation of the Escherichia coli dnaX programmed ribosomal frameshift signal in Salmonella typhimurium . Journal of Bacteriology . 179 . 13 . 4438–4442 . July 1997 . 9209069 . 179275 . 10.1128/jb.179.13.4438-4442.1997 .